Hyderabad varsity researchers develop nanomedicine for malaria

The new drug delivery system is equipped with a “time-temperature clock” module, where the doses for the treatment can be precisely tuned.

By Author  |  Published: 24th Feb 2018  3:55 pm
Malaria
File photo of Associate Professor of the School of Engineering Sciences and Technology, University of Hyderabad Pradip Paik (L) and Himadri Medhi, a PhD scholar with UoH (R)

Hyderabad: A research group led by Pradip Paik, Associate Professor of the School of Engineering Sciences and Technology, University of Hyderabad, has invented a new polymer-nanomedicine for treatment of Malaria.

Paik, presently on an assignment as Associate Professor of School of Biomedical Engineering, Indian Institute of Technology (BHU), Varanasi, and his research group have developed a new formulation of porous polymer capsules with commonly used antimalarial drugs that has shown ‘excellent’ anti-malarial activity.

The new drug delivery system is equipped with a “time-temperature clock” module, where the doses for the treatment can be precisely tuned. Paik reported that the new formulation was quite efficient in killing the P. falciparum infection in RBCs.

Paik, a pioneer in this technique, has proposed that this system is very unique and can be used further for animal trials. Himadri Medhi, a PhD scholar with UoH designed this nanomedicine with the support of other PhD scholars Somedutta Maity, Niranjan Suthram and Suresh Kumar Chalapareddy.

In a statement here, Paik also acknowledged the help of Mrinal Kanti Bhattacharyya of Department of Biochemistry, School of Life Sciences, University of Hyderabad for testing the effect of the nanomedicine on the in vitro culture of human malarial parasite P. falciparum suppression studies.