Sofiane Diop's header opened the scoring for the visitors in the sixth minute, and Guillermo Maripan doubled the lead with a side-footed finish in the second half after Ander Herrera failed to clear the ball, Xinhua news reports.
PSG moved three points clear of second-place Lille, which can move level on points by winning at fifth-place Rennes on Sunday but has a vastly inferior goal difference
Mbappe scored from the penalty spot in the 42nd minute against Istanbul Basaksehir on Wednesday, giving his side a three-goal lead at half-time after Neymar had already scored a brace.
The match, which started on Tuesday, had been halted after 14 minutes when both sides walked off amid alleged racist abuse from fourth official Sebastian Coltescu to Basaksehir coach Pierre Webo, reports Xinhua news agency.
The team didn't lose its discipline, its energy or the control of the ball. We played a good match and deserved to win, the club's official website quoted Tuchel as saying.
All the goals came in the second half, with Ander Herrera opening the scoring two minutes after the restart and Mbappe converting a 65th-minute spot-kick before Pablo Sarabia secured the points late on
Mbappe netted late to give France a 2-1 win at Croatia two days ago in the Nations League.
Nimes center half Loick Landre was sent off after 12 minutes for a chest-high high tackle on midfielder Rafinha.
