Hyderabad: ReaGene Biosciences bags emerging start-up award

A graduated startup company of ASPIRE-BioNEST incubator at UoH was identified as an emerging start-up company by an independent jury panel of ChemTech- Biopharma conference 2021

Hyderabad: ReaGene Biosciences Private Limited, a graduated startup company of ASPIRE-BioNEST incubator at the University of Hyderabad (UoH) was identified as an emerging start-up company by an independent jury panel of ChemTech- Biopharma conference 2021.

The award was in recognition of the unique 3D models being developed by its group companies, such as ReaGene Innovations Pvt Ltd, currently incubated at the ASPIRE-BioNEST, the UoH said in a press release on Wednesday.

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The models were focused on discovery of new products for high value unmet diseases such as sepsis and Covid-19, it said.

To date, majority of preclinical research was conducted on animals for both efficacy and toxicity, however, proved to be poorly translated to clinical outcomes. There was a strong need for better translational models to improve clinical translation and decrease clinical attrition rates.

Currently used in-vitro human single-cell static models do not mimic human physiology, cell-cell and organ-organ communications those play important role in drug efficacy and toxicity in humans in-vivo, the UoH said.

“ReaGene mission is to build proprietary humanised 3D proprietary tools containing multiple cell types of different organs to allow communications of different cell types and organs. These models represent closest to human in-vivo condition recapitulating human physiology to measure efficacy and toxicity simultaneously and make informed decisions on clinical liabilities before moving drugs into clinical trials. These models are much superior to organoids and spheroids to mimic human physiology and communications,” the UoH said.

Founders of ReaGene Biosciences and UoH alumnus, Dr Uday Saxena, and Dr Subrahmanyam Vangala expressed their happiness at the recognition and were hopeful that, the proprietary disruptive 3D bio printing platforms would revolutionise drug discovery research in India and rest of the world.

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