Tuesday, May 30, 2023
English News
  • Hyderabad
  • Telangana
  • Andhra Pradesh
  • India
  • World
  • Entertainment
  • Science and Tech
  • Sport
  • Business
  • ...
    • NRI
    • View Point
    • cartoon
    • Columns
    • Reviews
    • Education Today
    • Property
    • Videos
    • Lifestyle
    • Rewind
E-Paper
  • NRI
  • View Point
  • cartoon
  • Columns
  • Reviews
  • Education Today
  • Property
  • Videos
  • Lifestyle
  • Rewind
Home | Hyderabad | Vaccines Reduce Delta Severity Study

Vaccines reduce ‘Delta’ severity: Study

The rate of mortality was found to be about 50% lower in fully vaccinated individuals having a breakthrough infection, according to CCMB, AIg study

By M. Sai Gopal
Updated On - 12:36 AM, Mon - 19 July 21
Vaccines reduce ‘Delta’ severity: Study
Representational Image
whatsapp facebook twitter telegram

Hyderabad: For the first time, a Hyderabad-based study on the clinical outcomes of hospitalised breakthrough Covid infections has indicated that vaccines indeed helped in reducing severity and requirement for ventilator support among patients who tested positive for the Delta variant of SARS-CoV-2.

The hospital-based cohort study, which was a collaborative effort of the Centre for Cellular and Molecular Biology (CCMB) and Asian Institute of Gastroenterology (AIG), Hospitals, analysed clinical profiles and outcomes of 1,161 Covid patients between April 24 and May, when the second Covid wave was at its peak.

The study, which is available in the preprint form, included 1,161 Covid positive patients of which 495 patients were vaccinated either with Covaxin or Covishield while the remaining 666 patients were unvaccinated.

“Viral genome sequencing revealed that more than 90% of the patients in both the vaccinated and unvaccinated groups were harbouring the Delta variant of SARS-CoV-2. Vaccinated individuals showed higher neutralising antibodies and significantly decreased levels of Ferritin when compared to the unvaccinated group,” the study said.

Ferritin is a blood protein, which stores iron. Among Covid positive patients, several studies associate higher levels of Ferritin to cytokine storm, which causes mortality among Covid positive patients. The CCMB-AIG study has indicated that among breakthrough cases, Ferritin is found in decreased levels when compared to those who were unvaccinated.

“Severity of the disease and requirement of ventilator support were also significantly low in the vaccinated group despite the fact that individuals belonged to a significantly higher age group and risk factor. The rate of mortality was found to be about 50% lower in fully vaccinated individuals having a breakthrough infection. However, mortality in people who received a single dose was similar to the unvaccinated group,” according to the CCMB-AIG study.

The cohort study demonstrated that both Covishield and Covaxin are effective in preventing disease severity and mortality against Delta variant in completely vaccinated hospitalised patients, the researchers concluded. The CCMB-AIG study comes days after the pan-India demographic analysis of breakthrough Covid-19 infections on 677 patients, taken up by the Indian Council of Medical Research (ICMR), which has indicated that Covid vaccines are the best bet to reduce severity and fatalities among Covid-19 patients. In the ICMR study, only 9.9% of the breakthrough cases needed hospitalisation and the mortality was just 0.4%.

Also Read

Delta Covid strain dominant in Telangana

  • Follow Us :
  • Tags
  • Asian Institute of Gastroenterology (AIG)
  • Centre for Cellular and Molecular Biology (CCMB)
  • Covaxin
  • Covid vaccines

Related News

  • Here’s why some Covid patients continue to have difficulty in exercising

    Here’s why some Covid patients continue to have difficulty in exercising

  • Telangana government to provide booster dose from April 19

    Telangana government to provide booster dose from April 19

  • T-cell Covid vaccine may last longer than current jabs: Indian-American researcher

    T-cell Covid vaccine may last longer than current jabs: Indian-American researcher

  • Rise of Covid and influenza cases in India may lead to fatal?

    Rise of Covid and influenza cases in India may lead to fatal?

  • Covid on rise: SII restarts Covishield manufacturing

    Covid on rise: SII restarts Covishield manufacturing

  • Covid during pregnancy linked to brain disorders in infant boys

    Covid during pregnancy linked to brain disorders in infant boys

Latest News

  • Hyderabad team advance to semifinals of CM Cup Football Championship

    44 seconds ago
  • Pakistan: Imran Khan appears before anti-terrorism court, submits surety bonds in four cases

    11 mins ago
  • All support will be extended to Padmashri awardee Kanaka Raju: Asifabad Collector

    15 mins ago
  • Playing for India, winning 6 IPL titles my most cherished moments, says Rayudu on retirement

    20 mins ago
  • 22 MLAs, 9 MPs ‘unhappy’ with CM Shinde’s Shiv Sena, claims Shiv Sena-UBT

    30 mins ago
  • UWW condemns detention of wrestlers, threatens to ban WFI if polls not held in time

    32 mins ago
  • Osmania University tennis team settled for silver at Khelo India Games

    36 mins ago
  • ChatGPT can perform data analysis at fraction of human cost: Study

    40 mins ago

company

  • Home
  • About Us
  • Contact Us

business

  • Subscribe

telangana today

  • Telangana
  • Hyderabad
  • Latest News
  • Entertainment
  • World
  • Andhra Pradesh
  • Science & Tech
  • Sport

follow us

© Copyrights 2022 TELANGANA PUBLICATIONS PVT. LTD. All rights reserved. Powered by Veegam