AIIMS Bibinagar, AIIMS Bhopal identify potential therapeutic target for asthma

In a joint study by faculty of the AIIMS Bibinagar and Bhopal, it was found that asthma is associated with serum levels of IL-33 and correlated with the level of IgE and absolute eosinophil count.

Yadadri-Bhongir: In a joint study by faculty of the AIIMS Bibinagar and Bhopal, it was found that asthma is associated with serum levels of IL-33 and correlated with the level of IgE and absolute eosinophil count.

According to a press release from AIIMS Bibinagar, over 30 million people in India have asthma, but only 70 percent of them have a diagnosis. In the study, Researchers have explored the role of IL-33 in asthma pathophysiology. IL-33 is mainly released by necrosis of airway epithelial cells and activate mast cell that trigger the severity of Asthma . This study demonstrated that asthma is associated with serum levels of IL-33 and correlated with the level of IgE and absolute eosinophil count. Furthermore, IL-33 could play an important role in the clinical investigation of asthma.

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The research work was conducted by Associate professor in Biochemistry of Bibinagar AIIMs Dr. Rohit Saluja and doctors from microbiology department of Bhopal AIIMS.